Sorin Lab News

Spring 2012

Amethys! Physics undergrad Amethyst Radcliffe has been awarded a JPL Student Independent Research Internship for the Spring 2012 semester!

Richard Wang Graduating Computer Science undergrad Richard Wang has accepted a postition at Thales Avionics!

Fall 2011

Edsel Sorin Lab/Mezyk Lab alumnus Edsel Abud entered the joint M.D./Ph.D. program at UC Irvine this fall!

Erik Sorin Lab members Erik Carpio and Carolyn Kusaba presented their poster on collagen simulations at the CSULB Student Reseach Symposium

Spring 2011

Sam & Carolyn SorinLab students Samantha Cao and Carolyn Kusaba both received Women & Philanthropy Scholarships to support their summer research, marking the first time two Sorin Lab researchers have gotten this award at once!

Summer 2010

Yi An Sorin Lab Master's candidate Yi An has moved on to work on his Ph.D. in Chemistry at Texas A&M University!

news2010 Sorin Lab Alumnus Sarav Patel presented a poster at the regional AAAS meeting in OR on June 15th.

news2010 Ali DePaul gave an oral presentation at the recent local ACS meeting and is off to the UCSF Pharmacy program this fall!

About Our Research Group

Members of the Sorin Lab study the structure and dynamics of biological molecules via computer modeling and simulation. Using cluster computing and the Folding@Home Distributed Computing Project, we can apply a variety of models and methods to sample large numbers of independent simulations. Indeed, we are now capable of simulating some molecular events in dynamic equilibrium, making simulation a powerful tool with which to probe topics in molecular biology & drug design such as RNA folding, protein folding, drug binding, and membrane biophysics.

Sorin Lab December 2011


Recent Publications


gnra

Equilibrium Conformational Dynamics in an RNA Tetraloop from Massively Parallel Molecular Dynamics
Allison J. DePaul*, Erik J. Thompson*, Sarav S. Patel*, Kristin Haldeman*, & Eric J. Sorin (2010). Nucleic Acids Research. 38, 4856-4867.


Evaluating molecular mechanical potentials for helical peptides and proteins Erik J. Thompson*, Allison J. DePaul*, Sarav Patel*, & Eric J. Sorin (2010). PLoS One, 5, e10056, doi:10.1371/journal.pone.0010056.

Computer Simulations of Protein Folding
Vijay Pande, Eric J. Sorin, Christopher D. Snow, & Young Min Rhee (2008). Protein Folding, Misfolding and Aggregation: Classical Themes and Novel Approaches, Royal Society of Chemistry-Biomolecular Sciences.